Michigan State will return to Bloomington for the first time since 2018, having hosted Indiana in 2019 and then again in 2020 due to changes to the schedule as a result of COVID-19 and allowing the conference to better balance out home game slates each season for Michigan State and Michigan. The Spartans visit Memorial Stadium on Oct. 16 for a second straight road game after playing at Rutgers the week prior.
Source: The Only Colors